PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) treatments harness your body's natural healing properties by using concentrated platelets from your blood to rejuvenate skin, promote hair growth, and accelerate tissue repair.
PRP and PRF treatments use growth factors from a small sample of your blood, rich in platelets and white blood cells, to boost cell turnover and collagen production. This supports tissue repair, encouraging a youthful glow.
Pairing PRF and PRP with hyaluronic acid (HA) fillers enhances the benefits. HA fillers add volume, soften wrinkles, and smooth lines by filling in areas beneath the skin. They also enhance facial contours and add fullness to lips and cheeks. While HA provides volume, PRP/PRF injections improve skin quality from within by promoting healthy cell production and collagen synthesis for comprehensive rejuvenation. Our 4wellness St. Johns PRF and PRP injection specialists will work with you to determine the best treatment plan to give you the restorative look you're seeking.
Uses your own blood to support gentle facial and scalp rejuvenation
Can improve tone, texture, volume, and hair fullness over time
Appropriate for a wide range of skin tones and types
Stimulates collagen and tissue repair for gradual, lasting improvement
At our St Johns' location, PRP and PRF treatments help reduce wrinkles, enhance skin tone and texture, lighten dark spots, and promote hair growth.
Both use platelets from your own blood but differ in preparation and effectiveness. PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are autologous platelet concentrates. They release growth factors that aid tissue repair, stimulate collagen production, and encourage healthy cell turnover.
Injections often pair with microneedling to restore under-eye volume, refine skin texture, and address thinning hair.
Here's a comparison:
PRP is a platelet-rich plasma solution rich in growth factors such as VEGF, ideal for skin rejuvenation and hair growth.
PRF, as a second-generation concentrate, forms a gel-like fibrin matrix that gradually releases healing signals. This can provide better volume support and longer-lasting results.
Our location boasts over 15 years of combined expertise in skincare and cosmetic injectables. Schedule your complimentary consultation online or by phone, and your 4wellness specialist will craft a personalized plan for natural beauty enhancement and age defense.
Depending on your needs, they might suggest PRP injections for areas like the scalp (to support hair growth), under the eyes, or along fine lines and wrinkles. PRF treatment may also be recommended for gentle volume support, particularly under the eyes or along the jawline.
The process begins with a small blood draw. This sample is spun in a centrifuge to separate red and white blood cells, creating a platelet-rich serum for treatment.
Your 4wellness specialist will cleanse and prepare the area, then apply the serum using a fine needle or cannula. Mild swelling, tenderness, or redness might occur at injection sites, but most clients feel comfortable resuming daily activities soon after their appointment.
Your care continues beyond your visit. Before leaving, your specialist will provide clear aftercare instructions, explaining what to expect as your PRP or PRF treatment takes effect. You'll learn how to care for your skin, what's normal in the initial days, and when to reach out with questions.
A follow-up appointment is encouraged to assess your progress, review results in person, and adjust your long-term plan for smoother, youthful skin and overall health.
Initially explored in orthopedic and sports medicine, platelet-rich plasma (PRP) and leukocyte platelet-rich fibrin have gained popularity in cosmetic medicine for their skin-rejuvenating effects. These biological treatments leverage your body's natural healing power, offering an appealing option for those seeking organic enhancements without additional substances such as hyaluronic acid or cortisone.
With PRF injections or PRP injections, St. Johns patients can treat the following problem areas:
“PRP and PRF are great options to help with skin rejuvenation as they are rich in growth factors. PRP/PRF come from the patient’s own body, so it is a very natural way to help soften lines/wrinkles, build collagen, and help with dark coloring (especially under eyes).” - Maggie Bunch, APRN
These treatments do more than cover signs of aging; they support your skin's own repair process. Benefits may include:
Because platelet activation builds over time, many patients notice results that continue to improve for several weeks.
PRP or PRF injections can be ideal for healthy adults seeking natural-looking facial or scalp rejuvenation. However, if you have a blood disorder, clotting issues, chronic injuries, active skin infections, uncontrolled autoimmune diseases, or are taking medications that affect platelets or immunity, other treatments might be recommended.
Prior to any procedure, your 4wellness specialist will assess your health history and skin condition to create a personalized plan that aligns with your aesthetic goals and overall well-being.
Most people have very little downtime after platelet therapy. Mild bruising, swelling, or redness at the injection sites can occur and usually fades within 1–3 days. Many clients go back to work and normal routines right away.
For the first 24 hours, avoid strenuous exercise, direct sun, and harsh skincare treatments so your skin can start to recover. This regenerative injection works over time as stem cells and growth factors support tissue repair and renewal.
Most clients start to see visible changes in about three months, with full results developing over 6–12 months. The key benefits of PRF treatments include brighter, smoother, and healthier-looking skin. Many people notice firmer skin, a more even tone, and, for hair applications, thicker strands with less shedding.
Ongoing sessions every 4–6 months may be suggested to help maintain results, especially when used as part of an aging-prevention plan.
At our St. Johns location, your health and safety guide every decision. Your 4wellness specialist uses evidence-based techniques for all skin and wellness treatments, aiming for consistent, data-informed outcomes. Each visit centers on your goals, comfort, and confidence, all within a calming, spa-like setting that turns treatment time into true self-care.
Your experience at 4wellness begins with a detailed evaluation so your specialist can choose the right products and techniques for your skin and wellness needs. Our warm, professional team helps you feel at ease, answers questions clearly, and explains each step before moving forward. Every customized treatment is performed by skilled professionals who understand how to support long-term skin health and overall vitality.
4wellness focuses on effective, medical-grade treatments designed to refresh your appearance while respecting your features.
Your 4wellness specialist stays current with advances in aesthetic and wellness medicine, then applies proven, evidence-based techniques to build your treatment plan. This commitment to ongoing education supports consistent, predictable results over time.
After you leave the lounge, our care continues. We schedule follow-up visits to assess your progress, address questions, and adjust your plan as needed. During these check-ins, your 4wellness specialist evaluates your skin and body's response to ensure you feel informed and confident about your results.
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PRF injections can be used to treat a common type of hair loss called androgenic alopecia in both men and women. This treatment can help slow thinning, reduce shedding, and encourage new hair growth. PRF injections are also often used to support and enhance results after a hair transplant procedure.
Most clients need a series of 4–6 PRF hair sessions for noticeable improvement in density and coverage. Many people enjoy fuller, thicker hair for up to 24 months after a complete series. Because PRF is a temporary treatment, maintenance sessions are usually recommended to help you maintain your results over time.
The effects of PRF treatments typically last up to 12 months, while PRP injections often last about 6–9 months. During this time, many clients notice smoother skin texture, improved tone, softer fine lines, fuller lips, more hair growth, and a brighter under-eye area.
Because PRP and PRF are created from your own blood, these treatments are generally well tolerated for most healthy adults. Common side effects include temporary irritation, tenderness, pinpoint bleeding, redness, swelling, and bruising at the treatment sites. These effects usually improve within a few hours to a few days.
PRP and PRF serums contain growth factors that support healing and collagen production in the delicate under-eye area. Increased collagen can help thicken and firm the skin, which may reduce the look of dark circles and soften under-eye bags or creasing over time.
PRP and PRF can be used to improve several cosmetic concerns, including certain types of hair loss, acne scars, fine lines and wrinkles, hyperpigmentation, sun damage, stretch marks, uneven tone or texture, and mild skin laxity. Your 4wellness specialist will customize a plan based on your skin and goals.
Most clients describe PRP injections as mildly uncomfortable rather than painful. A topical numbing cream or other comfort measures can be applied before treatment to reduce sensitivity at the injection site and help you stay relaxed during the session.
